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ketamine necklace | gold vermeil meta-catalog small nuclear RNAs in theKetamine necklace 18K gold vermeil In 1962 Calvin Stevens at Parke Davis synthesised a compound he hoped would be a shorter acting dissociative than phencyclidine. In 2019 the FDA approved its S enantiomer for treatment resistant depression. Ketamine bookends two of the longest approval gaps in modern pharmacology. Worn here as a 27 mm 18K gold vermeil pendant. The Science Behind Ketamine Ketamine was first synthesised by Calvin Stevens at Parke Davis